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Xanthine

Low concern

Xanthine itself is a natural metabolite present at low levels in foods. Its methylated derivatives (caffeine, theobromine) are the bioactive forms.

Found in
7 products

What it is

A purine base, the precursor to caffeine, theobromine, and uric acid; occurs naturally in coffee/tea.

Naturally occurring metabolite; used in cosmetics and pharmaceuticals (e.g., theophylline derivatives).

Why it's flagged

What regulators actually say

"Caffeine, an example of methylxanthine, is GRAS for use as a food constituent."

Regulatory status

United States — FDA

Naturally occurring food constituent; specific derivatives like caffeine regulated under 21 CFR 182.1180.

European Union — EFSA

Naturally occurring food constituent.

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