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Sodium Metaphosphate
Sodium Metaphosphate
Moderate concern
Sodium metaphosphate is GRAS as a sequestrant. EFSA's 2019 re-evaluation of phosphates (E338-E452) lowered the ADI to 40 mg/kg bw/day (as P) and noted high consumers may exceed it, especially children.
Found in
42 products
What it is
Sodium metaphosphate — a polyphosphate; insoluble form (IMP) and sodium polymetaphosphate variants exist.
Sequestrant, emulsifier, dental polishing agent in toothpaste.
Why it's flagged
- EFSA 2019 lowered group ADI; high consumers may exceed it
- High dietary phosphate raises cardiovascular risk in CKD patients
What regulators actually say
"Sodium metaphosphate, insoluble — generally recognized as safe."
"The Panel established a group ADI of 40 mg/kg bw/day expressed as phosphorus for phosphates."
Regulatory status
United States — FDA
GRAS as miscellaneous additive (21 CFR 182.6760 / 182.1810).
European Union — EFSA
E452 authorised; EFSA 2019 set group ADI 40 mg/kg bw/day as P.
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