Sequestrant
'Sequestrant' is a generic functional class label rather than a specific compound. Specific sequestrants commonly used (e.g., EDTA, citrate, sodium phosphates) are individually authorized food additives with established ADIs.
What it is
Generic term for a chelating/metal-binding food additive (e.g., EDTA, citric acid, polyphosphates, tartrates) used to bind trace metals.
Chelates metal ions to prevent oxidation, discoloration, rancidity and loss of nutrients; preserves color and flavor.
Why it's flagged
- If polyphosphates: intake-of-concern for some populations
What regulators actually say
"Chelating agents, for example, EDTA, potassium tartrates, and potassium citrate, eliminate these negative effects by forming stable, normally water-soluble complexes of free metal ions."
Regulatory status
United States — FDA
Generic functional category; specific sequestrants regulated individually under 21 CFR (e.g., EDTA, citrate, phosphates)
European Union — EFSA
Generic functional category; individual compounds have E numbers and ADIs
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