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Schisandra Chinensis Seed Extract
Schisandra Chinensis Seed Extract
Moderate concern
Schisandra is permitted as a food/supplement ingredient but lacks a comprehensive safety dossier. EFSA novel-food status varies.
Found in
12 products
What it is
Extract from seeds/fruit of Schisandra chinensis; contains lignans (schisandrin) used in traditional Chinese medicine.
Botanical supplement; cosmetic active.
Why it's flagged
- Possible CYP450 drug interactions
- Limited modern toxicology data
What regulators actually say
"Schisandra has been used for liver protection but has been associated with rare cases of mild liver injury and may interact with hepatic CYP enzymes."
Regulatory status
United States — FDA
Permitted as dietary supplement; not a GRAS food additive
European Union — EFSA
Permitted in supplements; novel-food authorization assessed case-by-case
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