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Reishi Mushroom Extract

Also known as: Ganoderma lucidum extract, lingzhi extract

Low concern

Generally well tolerated at typical supplement doses. Case reports of liver toxicity exist with powdered preparations, and it may interact with anticoagulants and immunosuppressants.

What it is

Concentrated extract from the fruiting body or mycelium of Ganoderma lucidum, a medicinal mushroom.

Used as a functional/botanical ingredient marketed for immune and adaptogenic effects.

Why it's flagged

May interact with anticoagulant or antiplatelet medications
Rare reports of hepatotoxicity with powdered preparations
Health claims are not FDA-evaluated

Regulatory status

United States — FDA

Dietary ingredient (DSHEA); not approved as a drug

European Union — EFSA

Novel food considerations vary by preparation

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