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Proline
Proline
Low concern
L-Proline is GRAS as a nutrient and authorised in EU foods for particular nutritional uses. Endogenously synthesized in humans.
Found in
59 products
What it is
L-Proline, a non-essential proteinogenic amino acid abundant in collagen.
Flavor enhancer / nutritive amino acid; supplement ingredient.
Why it's flagged
- high-dose supplementation rarely studied
- hyperprolinemia patients should restrict intake
What regulators actually say
"Amino acids may be added to a food only in compliance with the requirements set forth in this section... L-Proline is permitted."
"EFSA Panel concluded that L-proline does not give rise to safety concerns at current levels of intake when used as flavouring."
Regulatory status
United States — FDA
GRAS as nutrient amino acid (21 CFR 172.320).
European Union — EFSA
Authorised amino acid for foods for particular nutritional uses; flavoring permitted.
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