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Polyaminopropyl Biguanide
Polyaminopropyl Biguanide
Moderate concern
PHMB is classified by the EU CLP as Carc. 2 (suspected human carcinogen by inhalation) and Acute Tox.
Found in
10 products
What it is
Cationic polymeric biguanide (PHMB), an antimicrobial preservative.
Not a food additive — used as a preservative/antimicrobial in cosmetics, contact-lens solutions, and disinfectants.
Why it's flagged
- EU classified suspected carcinogen by inhalation
- skin sensitizer
- not for food use
What regulators actually say
"PHMB is classified as Carc. 2 (suspected of causing cancer by inhalation) and the SCCS considers PHMB safe in cosmetic products at concentrations up to 0.1%, except for sprayable formulations."
Regulatory status
United States — FDA
Not approved as a food additive; regulated in some uses under EPA antimicrobial pesticide rules
European Union — EFSA
Not authorised in food; restricted in cosmetics (Annex V/III, EC 1223/2009)
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