Petroselinum Crispum Seed Extract
Parsley seed and seed extract contain apiole and myristicin, hepatotoxic and uterotonic compounds. FDA Poisonous Plant Database lists parsley seed/oil as toxic in concentrated form; large oral doses are abortifacient and can cause nephrotoxicity.
What it is
Extract of parsley (Petroselinum crispum) seeds; rich in apiole and myristicin.
Limited food use; FDA permits parsley as food but parsley seed/oil contains apiole/myristicin which raise toxicity concerns.
Why it's flagged
- Apiole and myristicin hepatotoxicity/nephrotoxicity
- Abortifacient at high doses
- Pregnancy contraindicated
What regulators actually say
"Parsley seed oil contains apiole and myristicin and has been associated with hepatic and renal toxicity at high doses."
Regulatory status
United States — FDA
Parsley herb GRAS as flavoring; concentrated parsley seed oil/extract not GRAS-listed and listed in FDA Poisonous Plant Database
European Union — EFSA
EU SCF: limit apiole/myristicin in foods; parsley oil restricted
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