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Pepperoni

Low concern

Pepperoni is processed (cured) meat. IARC classifies processed meat as Group 1 — carcinogenic to humans, based on sufficient evidence for colorectal cancer.

Found in
3,413 products

What it is

Cured, fermented, dried pork-and-beef sausage seasoned with paprika and chili. Contains added salt and typically nitrites/nitrates as curing agents.

Cured meat ingredient; provides flavor, color, and shelf stability via fermentation, drying, and curing salts.

Why it's flagged

What regulators actually say

"Processed meat was classified as carcinogenic to humans (Group 1), based on sufficient evidence in humans that the consumption of processed meat causes colorectal cancer."

IARC Press Release 240 — Carcinogenicity of red and processed meat — iarc.who.int

"Meat processing such as curing and smoking can result in formation of carcinogenic chemicals including N-nitroso compounds and polycyclic aromatic hydrocarbons."

Regulatory status

United States — FDA

Regulated as a meat product by USDA-FSIS; nitrite/nitrate use limited under 9 CFR 424.21.

European Union — EFSA

Cured meat is regulated; EFSA has lowered the ADI for nitrites (E 249–250) due to nitrosamine concerns.

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