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Paraxanthine

Moderate concern

Pharmacologically active stimulant similar to caffeine; isolated paraxanthine is a relatively novel ingredient with limited long-term safety data at supplement doses.

Found in

2 products

What it is

Methylxanthine and primary metabolite of caffeine in humans (1,7-dimethylxanthine); also used as a standalone stimulant ingredient.

Stimulant ingredient in some sports/energy supplements.

Why it's flagged

Cardiovascular and CNS effects similar to caffeine
Limited long-term safety data

What regulators actually say

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Regulatory status

United States — FDA

Notified to FDA via New Dietary Ingredient (NDI) submissions; specific products marketed as dietary supplements.

European Union — EFSA

Not specifically authorized as a novel food ingredient in the EU.

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