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Papain
Papain
Low concern
Papain is a GRAS enzyme used as a processing aid. It is generally well-tolerated; rare allergic reactions occur in latex- or papaya-sensitive individuals, and inhalational exposure has caused occupational asthma.
Found in
489 products
What it is
Cysteine proteolytic enzyme isolated from papaya (Carica papaya) latex/fruit.
Meat tenderizer, brewing clarifier, processing aid.
Why it's flagged
- Potential allergen in sensitive individuals
- Occupational respiratory sensitizer
What regulators actually say
"Papain (CAS Reg. No. 9001-73-4) is a proteolytic enzyme... GRAS when used in accordance with good manufacturing practice."
"EFSA scientific opinion on the safety evaluation of papain as a food enzyme."
Regulatory status
United States — FDA
GRAS — 21 CFR 184.1585
European Union — EFSA
Permitted as enzyme/processing aid
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