Pantethine
Pantethine converts to pantothenic acid in the body; pantothenic acid has no Tolerable Upper Intake Level set by NIH because no toxicity has been reported in humans. Mild gastrointestinal upset has been reported at gram-scale supplementation.
What it is
A dimer of pantothenic acid (vitamin B5) linked by cysteamine, used as a dietary supplement and metabolic precursor of coenzyme A.
Source of vitamin B5 activity in supplements; minor role in fortified foods.
Why it's flagged
- mild GI upset at high (10 g/day) doses
What regulators actually say
"Some individuals taking large doses of pantothenic acid supplements (e.g., 10 g/day) develop mild diarrhea and gastrointestinal distress... There are no reports of pantothenic acid toxicity in humans at high intakes."
Regulatory status
United States — FDA
Permitted in dietary supplements under DSHEA; not a recognized food fortificant in standard foods
European Union — EFSA
Pantothenic acid permitted as a vitamin source in food supplements
Scan it before you buy it
Get Ube on iOS or Android — point at any barcode, see what's actually in there.
Get the app