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Palmitoyl Pentapeptide-4

Safe

Palmitoyl pentapeptide-4 is a cosmetic peptide ingredient with no FDA food-additive approval and no established food-safety dossier. It is a non-food cosmetic chemical not intended for ingestion.

Found in
6 products

What it is

Palmitoyl pentapeptide-4 (Matrixyl) is a synthetic lipopeptide used as a cosmetic active ingredient, not a food substance.

Not used in food. Cosmetic active ingredient claimed for skin appearance.

Why it's flagged

What regulators actually say

"Palmitoyl Pentapeptide-4 is listed in the EU CosIng cosmetic ingredient database as a skin conditioning cosmetic ingredient."

Regulatory status

United States — FDA

Not approved as a food additive; cosmetic ingredient only.

European Union — EFSA

Not authorized as a food additive.

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