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Nootkatone

Low concern

Nootkatone is a naturally occurring citrus flavor compound; FEMA has assigned it GRAS status as a flavoring substance, and it is registered by EPA as an insect repellent active.

Found in
2 products

What it is

Nootkatone is a sesquiterpene ketone found naturally in grapefruit and Alaska yellow cedar; used as a flavor/fragrance and EPA-registered insect repellent.

Used as a natural flavoring substance for citrus/grapefruit flavor.

What regulators actually say

"Nootkatone is a natural, non-toxic compound found in cedar trees and grapefruit... Now that EPA has registered nootkatone, the compound can be used in the development of insect repellents and insecticides."

CDC NIOSH Update – EPA Registers Nootkatone — cdc.gov

Regulatory status

United States — FDA

FEMA GRAS flavoring substance (FEMA 3166)

European Union — EFSA

Listed in EU flavoring substances database

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