Natural Caffeine
FDA cites 400 mg/day as an amount not generally associated with negative effects in healthy adults; pregnant women are advised to limit intake to under 200 mg/day. Caffeine can cause anxiety, sleep disruption, and elevated heart rate at higher doses; sensitivity varies.
What it is
Caffeine extracted from natural sources such as coffee beans, tea leaves, or guarana.
Stimulant and bittering agent; provides alertness in beverages and supplements.
Why it's flagged
- sleep disruption
- anxiety
- elevated heart rate
- pregnancy risk above 200 mg/day
- not recommended for children/adolescents in high doses
What regulators actually say
"For most adults, the FDA has cited 400 milligrams a day...as an amount not generally associated with negative effects"
"Confirmed the safety of the 400 milligrams a day level for most adults"
Regulatory status
United States — FDA
GRAS for cola-type beverages (21 CFR 182.1180); other uses regulated
European Union — EFSA
Subject to labeling for high-caffeine beverages
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