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Melia Azadirachta Leaf Extract
Melia Azadirachta Leaf Extract
Moderate concern
Neem leaf extract contains bioactive limonoids. NIH NCCIH notes safety data for neem are limited and that ingestion (especially of neem oil) can be toxic, particularly to children.
Found in
10 products
What it is
Extract from leaves of neem (Azadirachta indica).
Cosmetic skin-conditioning/antimicrobial; some traditional medicinal use.
Why it's flagged
- Reported reproductive toxicity at high oral doses
- Hepatotoxicity reports per NCCIH
- Oral neem can be toxic, particularly to children
What regulators actually say
"Neem oil and neem extracts may cause severe adverse effects, especially in young children, including vomiting, drowsiness, seizures, and death."
Regulatory status
United States — FDA
Not GRAS as food additive; used in cosmetics
European Union — EFSA
Not authorised as a novel food
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