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Magnesium Bisglycinate

Also known as: Magnesium glycinate, Magnesium diglycinate

Low concern

Magnesium bisglycinate is a well-tolerated form of supplemental magnesium with good bioavailability. Excessive supplemental magnesium (above the UL of 350 mg/day from supplements for adults) can cause diarrhea and GI upset.

What it is

A chelated form of magnesium in which the mineral is bound to two molecules of the amino acid glycine.

Used as a dietary supplement and food fortificant; provides bioavailable magnesium with reduced gastrointestinal side effects compared to inorganic salts.

Why it's flagged

High supplemental doses can cause diarrhea or GI upset.
May interact with certain medications (antibiotics, bisphosphonates); individuals with kidney impairment should consult a clinician.

Regulatory status

United States — FDA

Permitted dietary supplement ingredient

European Union — EFSA

Authorised mineral source for food supplements (Regulation 1170/2009)

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