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Lysine
Lysine
Low concern
L-lysine is an essential amino acid GRAS in the US for nutrient fortification (21 CFR 172.320). EFSA and NIH consider it safe at typical dietary and supplement intakes.
Found in
145 products
What it is
L-lysine, an essential amino acid required for human protein synthesis.
Nutrient fortification; supplement; flavor enhancer in some products.
Why it's flagged
- GI upset at very high supplement doses
What regulators actually say
"Amino acids ... including L-lysine ... may be safely used in food when the amino acid is added in amounts to provide its nutritional benefits."
"The RDA for lysine for adults is 38 mg/kg per day."
Regulatory status
United States — FDA
GRAS for nutrient fortification under 21 CFR 172.320 (amino acids).
European Union — EFSA
Authorized as nutrient and feed additive.
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