Lactoferrin
Bovine lactoferrin is GRAS in the US for use in infant formula and other foods (multiple GRAS notices) and is authorized as a novel food in the EU. EFSA evaluated bovine lactoferrin and concluded that the proposed uses are safe.
What it is
Iron-binding glycoprotein found in milk and other secretions, isolated from bovine milk for food and supplement use.
Bioactive protein added to infant formula and supplements; antimicrobial and immunomodulatory functions.
Why it's flagged
- milk allergen
What regulators actually say
"GRAS Notice 000465 - Bovine milk-derived lactoferrin - FDA had no questions on the GRAS status."
"EFSA Scientific Opinion on bovine lactoferrin as a novel food ingredient."
Regulatory status
United States — FDA
GRAS (e.g., GRN 000077, GRN 000423, GRN 000465 for bovine lactoferrin).
European Union — EFSA
Authorized novel food in the EU.
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