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Hydrolyzed Vegetable Protein

Moderate concern

Acid-hydrolyzed vegetable protein (HVP) can contain 3-MCPD, a chloropropanol contaminant classified as a possible human carcinogen (IARC Group 2B) and reproductive toxicant in animals. FDA enforces a 1 ppm action limit; modern enzymatic HVP avoids 3-MCPD.

Found in
1,273 products

What it is

Plant protein (soy, corn, wheat) broken down via acid or enzymatic hydrolysis to release flavor-active amino acids and peptides.

Flavor enhancer providing umami/savory taste; alternative or complement to MSG.

Why it's flagged

What regulators actually say

"FDA considers acid-hydrolyzed protein containing more than 1 part per million (ppm) of 3-MCPD to be an unsafe food additive."

Regulatory status

United States — FDA

FDA considers acid-HVP with >1 ppm 3-MCPD an unsafe food additive (CPG 500.500).

European Union — EFSA

EFSA has set a TDI for 3-MCPD of 2 µg/kg bw/day; EU Regulation 2020/1322 sets max levels.

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