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Hydrolyzed Sodium Hyaluronate
Hydrolyzed Sodium Hyaluronate
Low concern
Hyaluronic acid and its salts are widely used in cosmetics and supplements. FDA has reviewed several GRAS notices for sodium hyaluronate without objection.
Found in
27 products
What it is
Lower molecular weight form of sodium hyaluronate produced by hydrolysis of hyaluronic acid.
Primarily a cosmetic humectant; in dietary supplements used for skin/joint claims.
Why it's flagged
- Limited evidence of meaningful benefit from oral hyaluronic acid for joint or skin outcomes
- Marketed claims often exceed evidence
What regulators actually say
"FDA has no questions at this time regarding the notifier's conclusion that sodium hyaluronate is GRAS under the intended conditions of use."
Regulatory status
United States — FDA
GRAS notices for sodium hyaluronate accepted with no questions; permitted as a dietary ingredient
European Union — EFSA
Permitted as a cosmetic ingredient and food supplement ingredient
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