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Honokiol
Honokiol
Moderate concern
Honokiol is a bioactive compound studied for anxiolytic and antimicrobial effects. Long-term human safety data limited; potential for drug interactions and CNS effects.
Found in
4 products
What it is
A polyphenolic compound isolated from Magnolia bark.
Used in dietary supplements, oral care, and traditional medicine; not commonly added to food.
Why it's flagged
- limited human safety data
- potential drug interactions
- CNS effects
What regulators actually say
"Honokiol exhibits a range of pharmacological activities; further studies are needed to establish safety profile in humans."
Regulatory status
United States — FDA
Not a recognized food additive
European Union — EFSA
Not authorized as novel food
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