Heliotropine
Piperonal/heliotropine is FEMA GRAS #2911 and listed in 21 CFR 182.60 as a synthetic flavoring substance generally recognized as safe when used at flavor levels. JECFA also evaluated it without safety concerns at intake levels typical of food use.
What it is
Heliotropine (piperonal, CAS 120-57-0) — a benzodioxole aromatic aldehyde with a vanilla/cherry-floral aroma.
Flavoring substance.
What regulators actually say
"Piperonal (FEMA# 2911, CAS# 120-57-0) — assigned FEMA GRAS Number 2911."
"21 CFR 182.60 lists synthetic flavoring substances generally recognized as safe when used at appropriate levels, including piperonal."
Regulatory status
United States — FDA
FEMA GRAS #2911; listed in 21 CFR 182.60 as a synthetic flavoring substance
European Union — EFSA
Permitted flavoring substance (FL no. 13.012)
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