Griffonia
Also known as: griffonia simplicifolia
Griffonia simplicifolia seed extract contains 5-HTP, a serotonin precursor. It is sold as a dietary supplement; FDA has historically had concerns about 5-HTP contamination (Peak X) linked in the past to eosinophilia-myalgia-like cases.
What it is
Seed extract of Griffonia simplicifolia, a natural source of 5-hydroxytryptophan (5-HTP) used as a dietary supplement.
Used in dietary supplements as a source of 5-HTP, not as a conventional food additive.
Why it's flagged
- 5-HTP contamination history
- interaction with serotonergic drugs
What regulators actually say
"5-HTP is sold as a dietary supplement to be used as an antidepressant, appetite suppressant, and sleep aid. Concerns about contaminants (Peak X) similar to those linked to EMS in L-tryptophan have been raised."
Regulatory status
United States — FDA
Marketed as dietary supplement; not a food additive
European Union — EFSA
Not authorized as novel food ingredient
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