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Grapefruit Pulp

Low concern

Grapefruit pulp provides fiber, vitamin C, and lycopene. Grapefruit furanocoumarins inhibit intestinal CYP3A4, potentially elevating plasma concentrations of many medications, including statins, calcium channel blockers, and certain immunosuppressants.

Found in

74 products

What it is

Pulp portion of grapefruit (Citrus paradisi) including juice sacs and membranes.

Texture and fiber in juice products; whole-fruit-like ingredient.

Why it's flagged

drug-grapefruit CYP3A4 interactions

What regulators actually say

"Grapefruit juice can affect the action of some prescription medicines as well as a few non-prescription medications."

FDA — Grapefruit Juice and Some Drugs Don't Mix — fda.gov

Regulatory status

United States — FDA

Conventional whole-food component.

European Union — EFSA

Conventional whole-food component.

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