Glycyrrhiza Glabra Rhizome/Root Extract
Licorice extract contains glycyrrhizin, which can cause pseudoaldosteronism (sodium retention, potassium loss, hypertension) at chronic high doses. FDA warns adults against eating large amounts of black licorice.
What it is
Extract from the root and rhizome of Glycyrrhiza glabra (licorice), containing glycyrrhizin (glycyrrhizic acid) and flavonoids.
Sweetener, flavoring (50x sweeter than sucrose), and traditional botanical.
Why it's flagged
- hypertension
- hypokalemia
- pseudoaldosteronism
- drug interactions
What regulators actually say
"If you're 40 or older, eating 2 ounces of black licorice a day for at least two weeks could land you in the hospital with an irregular heart rhythm or arrhythmia."
Regulatory status
United States — FDA
GRAS as a flavoring (21 CFR 184.1408 - licorice and licorice derivatives); FDA consumer alert on black licorice
European Union — EFSA
EFSA: regular intake should not exceed 100 mg/day of glycyrrhizin
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