Glucosamine
Glucosamine is a widely consumed supplement with broadly favorable safety record; not approved by FDA as a drug for joint conditions. Shellfish-derived forms can pose allergen risk.
What it is
An amino sugar (2-amino-2-deoxy-D-glucose) naturally present in connective tissue, derived commercially from shellfish chitin or fermented corn.
Dietary supplement ingredient marketed for joint health; sometimes used in functional foods.
Why it's flagged
- shellfish allergen (if shellfish-derived)
- mild GI effects at high doses
What regulators actually say
"Glucosamine sulfate and glucosamine hydrochloride are dietary supplements that have been studied primarily for osteoarthritis."
Regulatory status
United States — FDA
Permitted as a dietary supplement ingredient under DSHEA; not an approved food additive for general food use.
European Union — EFSA
Authorized for use in food supplements; novel food status varies by source.
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