Glucosamine Sulfate
Glucosamine sulfate is widely sold as a dietary supplement and is regulated under DSHEA in the US. Studies (e.g., the GAIT trial) found generally good safety; commonly derived from shellfish, raising allergen considerations.
What it is
An amino sugar (glucosamine) as the sulfate salt, often derived from shellfish or fermentation.
Dietary supplement ingredient marketed for joint health; not a typical food additive.
Why it's flagged
- shellfish allergen if shellfish-derived
- limited evidence of clinical efficacy
What regulators actually say
"Glucosamine and chondroitin... are sold as dietary supplements for osteoarthritis. Studies have found mixed results on effectiveness, and the supplements are generally considered safe."
Regulatory status
United States — FDA
dietary supplement ingredient (DSHEA)
European Union — EFSA
permitted in food supplements; not a general food additive
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