Garcinia Cambogia Fruit Extract
Garcinia cambogia extract has been associated with hepatotoxicity, including reports of acute liver failure requiring transplant. NIH LiverTox documents multiple cases.
What it is
Extract from the rind of Garcinia gummi-gutta (formerly G. cambogia), standardized to hydroxycitric acid (HCA), marketed as a weight-loss supplement.
Botanical supplement ingredient.
Why it's flagged
- hepatotoxicity / liver injury
- weak efficacy
What regulators actually say
"Garcinia cambogia has been implicated in cases of clinically apparent acute liver injury, some severe and resulting in acute liver failure."
"FDA has identified weight loss products containing hidden drug ingredients including Garcinia cambogia products as tainted."
Regulatory status
United States — FDA
Marketed as dietary supplement; FDA has issued safety warnings
European Union — EFSA
No authorized health claim; safety concerns noted
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