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Ergothioneine

Low concern

Naturally present in many edible foods; FDA issued no-questions GRAS Notice (GRN 734) for synthetic L-ergothioneine for specified food uses. EFSA approved as a novel food.

Found in
2 products

What it is

Naturally occurring sulfur-containing amino acid antioxidant produced primarily by fungi; abundant in mushrooms.

Endogenously consumed antioxidant via dietary mushrooms; sometimes used as a fortificant or supplement.

What regulators actually say

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Regulatory status

United States — FDA

GRAS Notice GRN 734 received 'no questions' letter for L-ergothioneine.

European Union — EFSA

Authorized as a novel food ingredient under EU Regulation 2017/2470.

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