Home › Disodium Inosinate

Disodium Inosinate

Also known as: E631, Sodium inosinate

Low concern

Disodium inosinate is FDA GRAS and EFSA-authorized. JECFA assigned ADI "not specified." Concern is largely limited to gout/hyperuricemia patients: as a purine, it can contribute to uric acid load.

Found in

15,269 products

E-number

E631

What it is

Disodium inosinate (IMP), a flavor-enhancing nucleotide derived from meat, fish, or fermentation. Used synergistically with MSG.

Flavor enhancer (umami); synergistic with MSG (E621) and disodium guanylate (E627).

Why it's flagged

Purine load — caution in gout/hyperuricemia patients
Often derived from meat/fish (allergen, not vegetarian)

What regulators actually say

"Disodium inosinate is permitted as a direct food additive used as a flavor enhancer."

21 CFR 172 - Food additives permitted for direct addition (eCFR) — ecfr.gov

Regulatory status

United States — FDA

GRAS as flavor enhancer (21 CFR 172.535)

European Union — EFSA

Authorized as E631; ADI not specified

Scan it before you buy it

Get Ube on iOS or Android — point at any barcode, see what's actually in there.

Get the app