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Guanylic Acid

Also known as: E626, guanosine monophosphate, guanosine-5'-monophosphate, guanosine 5'-phosphoric acid, GMP

Low concern

Authorized flavor enhancer; EFSA established a group ADI 'not specified' for ribonucleotide flavor enhancers, indicating no safety concern at intended use levels.

Found in

2 products

E-number

E626

What it is

Guanylic acid (5'-guanosine monophosphate, GMP), a nucleotide used as a flavor enhancer.

Flavor enhancer that produces umami taste, often used with monosodium glutamate.

Why it's flagged

may be of concern for those with severe gout (purine metabolite)

What regulators actually say

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Regulatory status

United States — FDA

Permitted as a food additive; functions as flavor enhancer

European Union — EFSA

Re-evaluated 2021; no safety concern at reported uses

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