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Calcium Dihydrogen Diphosphate

Also known as: E450vii, Acid calcium pyrophosphate, E450

Moderate concern

Calcium dihydrogen diphosphate is an authorized phosphate additive. EFSA's 2019 re-evaluation set a group ADI for phosphates of 40 mg/kg bw/day as P, and noted exposure may exceed this in children.

Found in

63 products

E-number

E450

Type

emulsifier, humectant, sequestrant, stabiliser, thickener

What it is

Calcium dihydrogen diphosphate (E450(vii)) — a calcium phosphate salt used as a food additive.

Acidulant, leavening agent, and emulsifier/stabilizer; common in baked goods.

Why it's flagged

Cumulative phosphate intake may exceed ADI in some populations

What regulators actually say

"The Panel established a group acceptable daily intake (ADI) for phosphates of 40 mg/kg body weight per day, expressed as phosphorus."

EFSA – Re-evaluation of phosphates (2019) — efsa.europa.eu

Regulatory status

United States — FDA

Calcium phosphates GRAS under 21 CFR 184.1.

European Union — EFSA

Authorized; group ADI 40 mg/kg bw/day as P.

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