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Trisodium Diphosphate

Also known as: E450ii, e450ii, E450

Low concern

Diphosphates including trisodium diphosphate (E450(ii)) are authorized food additives in the EU and the US; EFSA's 2019 re-evaluation set a group ADI for phosphates of 40 mg/kg bw/day expressed as phosphorus.

Found in

1 products

E-number

E450

Type

emulsifier, humectant, sequestrant, stabiliser, thickener

What it is

Trisodium diphosphate (E450(ii)), a sodium salt of pyrophosphoric acid used as an emulsifier, sequestrant, leavening acid, and pH buffer in food.

Emulsifier, leavening agent, sequestrant, and buffer.

Why it's flagged

Contributes to total dietary phosphate intake, which may be relevant for individuals with chronic kidney disease.

What regulators actually say

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Regulatory status

United States — FDA

Sodium pyrophosphates including trisodium diphosphate are GRAS (21 CFR 182.1810; 21 CFR 182.6789).

European Union — EFSA

Authorized as E450(ii) under Regulation (EC) No 1333/2008; included in EFSA 2019 group ADI for phosphates.

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