Thiodipropionic Acid
Also known as: E388
Thiodipropionic acid (E388) and its dilauryl ester (E389) are no longer authorized as food additives in the EU (delisted from the food additive list in 2008–2011). The FDA still permits thiodipropionic acid as an antioxidant in foods at limited levels under 21 CFR 172.140.
What it is
Thiodipropionic acid; a sulfur-containing dicarboxylic acid used as a synthetic antioxidant.
Antioxidant in fats and oils, formerly used to prevent rancidity.
Why it's flagged
- EU authorization withdrawn
- limited toxicity data prompted EU delisting
What regulators actually say
"Thiodipropionic acid... may be safely used as an antioxidant in food, in an amount not in excess of that reasonably required to produce its intended effect."
"Regulation 1129/2011 establishes the Union list of food additives approved for use in food; thiodipropionic acid (E 388) is not included in the Union list."
Regulatory status
United States — FDA
Permitted as a food antioxidant under 21 CFR 172.140 (use ≤0.02% by weight of fat content).
European Union — EFSA
No longer authorized as a food additive in the EU.
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