Dicalcium Phosphate
Also known as: E341ii, Dibasic calcium phosphate, di-calcium phosphate, E 341ii, E-341ii
EFSA's 2019 re-evaluation of phosphates (E 338–341, E 343, E 450–452) established a group ADI of 40 mg/kg bw/day expressed as phosphorus and noted that dietary exposures can exceed the ADI for high consumers. The Panel did not identify genotoxicity or carcinogenicity concerns.
What it is
Dicalcium phosphate (calcium hydrogen phosphate, CaHPO4), an inorganic calcium-phosphorus compound.
Calcium fortificant, leavening acid, dough conditioner, and anti-caking agent.
Why it's flagged
- high cumulative phosphate intake may exceed ADI
- concern for individuals with kidney impairment
What regulators actually say
"The Panel derived a group acceptable daily intake (ADI) for phosphates expressed as phosphorus of 40 mg/kg body weight (bw) per day... dietary exposure to phosphates may exceed the ADI in infants, toddlers and children with mean exposure as well as in some highly exposed adults."
"Calcium phosphate, dibasic (CaHPO4·2H2O)... is generally recognized as safe when used in accordance with good manufacturing practice."
Regulatory status
United States — FDA
GRAS under 21 CFR 184.1217.
European Union — EFSA
Re-evaluated by EFSA in 2019 — group ADI 40 mg/kg bw/day as P; high consumers may exceed ADI.
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