Calcium Phosphates
Also known as: E341, calcium phosphate, E 341, E-341, Calcium phosphate
Calcium phosphates are FDA GRAS and EFSA-authorized as E341(i, ii, iii). Group phosphate ADI of 40 mg/kg bw/day expressed as phosphorus (EFSA 2019).
What it is
Group of calcium phosphate compounds (mono-, di-, and tribasic calcium phosphate) used in foods.
Anticaking agent, calcium fortificant, leavening agent, dough conditioner, pH regulator.
Why it's flagged
- cumulative phosphate burden in CKD patients
- potential nanoparticle content noted in some food-grade material
What regulators actually say
"Calcium phosphate (mono-, di-, and tribasic) - generally recognized as safe when used as a nutrient or dietary supplement."
"The Panel derived a group acceptable daily intake (ADI) for phosphates expressed as phosphorus of 40 mg/kg body weight per day."
Regulatory status
United States — FDA
GRAS under 21 CFR 182.5223 / 182.8223 (calcium phosphates).
European Union — EFSA
Authorized as E341(i, ii, iii); group phosphate ADI 40 mg/kg bw/day as phosphorus.
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