Tripotassium Phosphate
Also known as: E340iii, E 340iii, E340 iii, E-340iii, Tribasic potassium phosphate
Tripotassium phosphate is GRAS for food use. Phosphate additives have raised concerns at high cumulative intakes — observational evidence links high phosphate intake from additives to cardiovascular and kidney effects, particularly in CKD patients.
What it is
Tripotassium phosphate (K3PO4); inorganic potassium phosphate salt used as buffer and emulsifier.
Acidity regulator, emulsifier, sequestrant; potassium fortificant.
Why it's flagged
- cumulative phosphate load may stress kidneys (especially CKD)
- linked to cardiovascular events in observational studies
What regulators actually say
"Potassium phosphate (mono-, di-, tribasic)... is generally recognized as safe when used in accordance with good manufacturing practice."
"The Panel concluded that an ADI for phosphates expressed as phosphorus of 40 mg/kg bw per day could be established."
Regulatory status
United States — FDA
GRAS (21 CFR 182.1628 potassium phosphate).
European Union — EFSA
Approved (E 340); group ADI of 40 mg P/kg bw/day for phosphates established in 2019.
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