Lipase
Also known as: E1104
Lipases are widely used food enzymes. EFSA has issued positive safety opinions for multiple lipase preparations from microbial sources.
What it is
Lipase, an enzyme that hydrolyzes triglycerides; produced from animal pancreas or microbial fermentation.
Processing aid/enzyme used in cheese, dairy, and baked products.
Why it's flagged
- potential allergen if from porcine/bovine pancreas (rare)
What regulators actually say
"EFSA evaluated the safety of a lipase produced with a strain of Aspergillus oryzae and concluded its use in foods does not give rise to safety concerns."
"FDA inventory of GRAS notices includes multiple lipase preparations from microbial fermentation."
Regulatory status
United States — FDA
Various lipase preparations GRAS (e.g., GRN-listed) or affirmed under 21 CFR 184.
European Union — EFSA
Multiple lipase preparations authorized under enzyme regulation 1332/2008; legacy E1104 not listed in current EU additives database.
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