Protease
Also known as: E1101, peptidase, proteinase, EC 3.4, E-1101
Proteases are enzymes used as processing aids and are generally inactivated during processing. EFSA and FDA have evaluated multiple protease preparations as safe for their intended uses.
What it is
Proteases are enzymes that hydrolyze peptide bonds in proteins; E1101 covers various microbial and animal-derived protease preparations.
Enzyme/processing aid for tenderizing meat, dough conditioning, brewing, dairy.
Why it's flagged
- potential allergenicity for occupational handlers
What regulators actually say
"Mixed carbohydrase and protease enzyme product. The ingredient is generally recognized as safe."
"This Regulation lays down rules on food enzymes used in foods... ensuring the effective functioning of the internal market and a high level of protection of human health."
Regulatory status
United States — FDA
Multiple proteases are GRAS (e.g., 21 CFR 184.1027 for mixed carbohydrase/protease)
European Union — EFSA
Regulated as food enzymes under EU Regulation 1332/2008
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