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Cyclodextrin
Cyclodextrin
Low concern
Cyclodextrins (alpha, beta, gamma) are approved food ingredients. FDA has GRAS notifications for all three forms.
Found in
57 products
What it is
Cyclic oligosaccharides (alpha-, beta-, or gamma-cyclodextrin) made by enzymatic conversion of starch.
Carrier and stabilizer for flavors and colors; encapsulation agent; reduces cholesterol in dairy.
Why it's flagged
- May cause gastrointestinal symptoms at very high intakes
What regulators actually say
"FDA has no questions regarding the conclusion that gamma-cyclodextrin is GRAS under intended conditions of use."
"The Panel established an ADI of 5 mg/kg bw/day for beta-cyclodextrin (E 459)."
Regulatory status
United States — FDA
GRAS notice received for alpha-, beta-, and gamma-cyclodextrin
European Union — EFSA
Approved E459 (beta-cyclodextrin); ADI established at 5 mg/kg bw/day
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