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Cholecalciferol
Cholecalciferol
Also known as: vitamin D3, D3
Low concern
Cholecalciferol is FDA-approved for vitamin D fortification under 21 CFR 184.1950 and is essential for calcium homeostasis. NIH defines a Tolerable Upper Intake Level of 100 mcg (4,000 IU)/day for adults; chronic excessive intake can cause hypercalcemia.
Found in
25,643 products
What it is
Vitamin D3, the form of vitamin D synthesized in skin from UVB exposure or obtained from animal sources.
Vitamin D fortificant in dairy and plant-based milks.
Why it's flagged
- hypercalcemia risk at chronic high supplemental doses (well above food fortification levels)
What regulators actually say
"The Food and Nutrition Board has set a tolerable upper intake level of 100 mcg (4,000 IU) per day for adults; intakes above this can cause hypercalcemia."
Regulatory status
United States — FDA
GRAS for fortification (21 CFR 184.1950)
European Union — EFSA
Permitted as fortificant
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