Cellulose Gel and Cellulose Gum
Also known as: microcrystalline cellulose, carboxymethyl cellulose, MCC, CMC, E460
Both components are FDA-approved food additives considered safe at typical exposure. Recent rodent and small human studies suggest that emulsifying cellulose derivatives, particularly CMC, may alter gut microbiota and intestinal barrier function in susceptible individuals; the evidence is not yet definitive in humans.
What it is
A combination of microcrystalline cellulose (insoluble plant fiber) and cellulose gum (carboxymethyl cellulose), both derived from purified plant cellulose.
Used together as a stabilizer, thickener, and texturizer to mimic fat and prevent ingredient separation in low-fat dairy, sauces, and frozen desserts.
Why it's flagged
- Emerging research suggests CMC may affect gut microbiome and intestinal lining
- Provides bulk and texture but no nutritional value
Regulatory status
United States — FDA
GRAS (21 CFR 182.1745, 21 CFR 182.70)
European Union — EFSA
Authorised food additives E460, E466
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