Calcium Saccharin
Permitted in the US (delisted from NTP carcinogen report in 2000 after rodent-specific mechanism was discounted) and in the EU as E954. Earlier warning labels were rescinded by Congress in 2000.
What it is
Calcium salt of saccharin, a non-nutritive sweetener ~300x sweeter than sucrose.
High-intensity sweetener in tabletop sweeteners, beverages, and foods for low-calorie use.
Why it's flagged
- historical bladder cancer concerns based on rat studies later deemed not relevant to humans
What regulators actually say
"Saccharin, ammonium saccharin, calcium saccharin, and sodium saccharin may be safely used in food in accordance with the following prescribed conditions."
"The Panel established an ADI of 5 mg/kg bw per day for saccharin and its sodium, potassium and calcium salts (E 954), expressed as free imide."
Regulatory status
United States — FDA
Permitted under 21 CFR 180.37 (saccharin and its calcium, potassium, and sodium salts).
European Union — EFSA
Approved as E954 under Regulation 1333/2008; ADI 5 mg/kg bw/day.
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