Calcium Fructoborate
Calcium fructoborate is sold as a dietary supplement; FDA has not formally affirmed its GRAS status. EFSA has set a Tolerable Upper Intake Level for boron of 10 mg/day for adults — supplemental intake should be considered against this UL, since boron exceeding tolerable levels is associated with reproductive toxicity in animals.
What it is
Calcium fructoborate is a sugar-borate complex of fructose, calcium, and boron used as a dietary supplement source of bioavailable boron.
Source of boron and calcium in dietary supplements.
Why it's flagged
- Boron has a Tolerable Upper Intake Level of 10 mg/day; high supplement use can approach this
What regulators actually say
"The Panel established a Tolerable Upper Intake Level for boron of 10 mg/day for adults including pregnant and lactating women."
Regulatory status
United States — FDA
Marketed as dietary supplement under DSHEA; no FDA GRAS notice
European Union — EFSA
Boron UL set at 10 mg/day for adults
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