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Calcium Bisglycinate

Low concern

Calcium glycinate/bisglycinate is a chelated calcium source recognized as a permitted nutrient source by EFSA and used in food fortification. Calcium intake supports bone health; excessive intake (above the UL of 2,500 mg/day for adults) is associated with kidney stones and possible cardiovascular concerns.

Found in
10 products

What it is

Calcium chelated with two glycine molecules (calcium bisglycinate), a chelated mineral supplement form.

Calcium fortificant in foods, beverages, and supplements.

Why it's flagged

What regulators actually say

"The Tolerable Upper Intake Level for calcium for adults is 2,500 mg/day, falling to 2,000 mg/day for those over 50."

"The Panel concludes that the use of calcium bisglycinate as a source of calcium ... is not of safety concern."

Regulatory status

United States — FDA

Calcium salts of amino acids generally permitted as nutrient sources/dietary supplements; broader calcium fortification at 21 CFR 184.1191 (calcium glycerophosphate) and related sections.

European Union — EFSA

Calcium bisglycinate authorized as a source of calcium for foods (EFSA opinion 2014).

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