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Bupleurum Falcatum Root Extract

Moderate concern

Bupleurum falcatum is a traditional medicinal herb. Cases of hepatotoxicity have been reported with bupleurum-containing products; it is not a routine food ingredient.

Found in
2 products

What it is

Extract of the root of Bupleurum falcatum, a herb used in traditional East Asian medicine (chai hu).

Not a typical food; used in traditional herbal medicine and supplements.

Why it's flagged

What regulators actually say

"Sho-saiko-to is an herbal mixture used in traditional Asian medicine that contains bupleurum (chai hu)... has been linked to instances of clinically apparent acute liver injury."

Regulatory status

United States — FDA

Not listed as a food additive; sold as dietary supplement

European Union — EFSA

No food evaluation located

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