Bromelain
Bromelain is a generally recognized as safe enzyme widely used as a processing aid. It can cause mild GI upset and rarely allergic reactions in pineapple-sensitive individuals; supplemental doses may interact with anticoagulant medication.
What it is
Mixture of proteolytic (protein-digesting) enzymes extracted from pineapple stem and fruit.
Meat tenderizer, brewing/baking processing aid, dietary supplement.
Why it's flagged
- Allergy in pineapple-sensitive individuals
- Possible bleeding interaction with anticoagulants at supplement doses
What regulators actually say
"Bromelain (CAS Reg. No. 9001-00-7) is a protease enzyme preparation derived from the pineapple plant... GRAS."
"Bromelain is a mixture of proteolytic enzymes derived from the pineapple plant; therapeutic applications and safety considerations are reviewed."
Regulatory status
United States — FDA
GRAS — 21 CFR 184.1024
European Union — EFSA
Permitted as enzyme/processing aid
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