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Beta-Caryophyllene

Low concern

Beta-caryophyllene occurs naturally in many edible plants and is FEMA GRAS at typical flavoring use levels. No notable safety signals at dietary intake.

Found in
5 products

What it is

A bicyclic sesquiterpene found naturally in clove, black pepper, hops, rosemary, and cannabis; FEMA GRAS flavor ingredient (FEMA 2252).

Flavoring/fragrance compound — spicy, woody notes.

What regulators actually say

"Caryophyllene is listed among synthetic flavoring substances and adjuvants permitted for direct addition to food for human consumption."

Regulatory status

United States — FDA

FEMA GRAS (FEMA 2252); used as a synthetic flavoring substance

European Union — EFSA

Authorized flavoring (FL no. 01.007)

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