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Bacillus Subtilis

Low concern

Generally considered safe; certain strains have been affirmed as GRAS by FDA for use as direct food ingredients and as enzyme sources.

Found in
151 products

What it is

A Gram-positive, rod-shaped bacterium used as a probiotic and as a source of food enzymes.

Probiotic culture; source of enzymes (e.g., proteases, amylases) used in food processing.

What regulators actually say

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Regulatory status

United States — FDA

GRAS for specific strains via GRAS notices

European Union — EFSA

QPS status (Qualified Presumption of Safety) for specific strains

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